Tumour necrosis factor receptor superfamily member 11B polymorphisms and association with knee osteoarthritis in women

Hulin-Curtis, Sarah L ORCID: https://orcid.org/0000-0003-0889-964X, Bidwell, JL and Perry, MJ (2012) Tumour necrosis factor receptor superfamily member 11B polymorphisms and association with knee osteoarthritis in women. International Journal of Immunogenetics, 39 (3). pp. 207-209. doi:10.1111/j.1744-313X.2012.01083.x

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Abstract

We examined single-nucleotide polymorphisms (SNPs) across the tumour necrosis factor receptor superfamily member 11B (TNFRSF11B) gene and knee OA. We identified alleles in a VNTR region in intron 3 that was observed exclusively in women OA cases (P = 0.007, Pc = 0.042). Our results reveal that a previously unreported association between a VNTR genotype in TNFRSF11B and knee OA in women.

Item Type:	Article
Article Type:	Article
Subjects:	R Medicine > R Medicine (General)
Divisions:	Schools and Research Institutes > School of Education, Health and Sciences
Research Priority Areas:	Health, Life Sciences, Sport and Wellbeing
Depositing User:	Sarah Curtis
Date Deposited:	18 Jun 2024 13:32
Last Modified:	05 Aug 2025 09:54
URI:	https://eprints.glos.ac.uk/id/eprint/14155

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