Association between CCL2 haplotypes and knee osteoarthritis

Hulin-Curtis, Sarah L ORCID: 0000-0003-0889-964X, Bidwell, JL and Perry, MJ (2012) Association between CCL2 haplotypes and knee osteoarthritis. International Journal of Immunogenetics, 40 (4). pp. 280-283. doi:10.1111/iji.12015

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Abstract

We examined five single nucleotide polymorphisms (SNPs) and reconstructed 5-locus haplotypes of the CCL2 gene, in knee osteoarthritis (OA) cases and in controls. The CCL2 rs2857657 variant (G) allele was observed more frequently in female knee OA cases than in controls. One haplotype (H5) was observed exclusively in the control group (f = 2.3%). Genetic variation in the CCL2 gene may be associated with knee OA.

Item Type:	Article
Article Type:	Article
Subjects:	R Medicine > R Medicine (General)
Divisions:	Schools and Research Institutes > School of Education and Science
Research Priority Areas:	Health, Life Sciences, Sport and Wellbeing
Depositing User:	Sarah Curtis
Date Deposited:	18 Jun 2024 13:31
Last Modified:	18 Jun 2024 13:31
URI:	https://eprints.glos.ac.uk/id/eprint/14152

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