Avian NK activities, cells and receptors.

Rogers, Sally L, Viertlboeck, Birgit C, Göbel, Thomas W and Kaufman, Jim (2008) Avian NK activities, cells and receptors. Seminars in Immunology, 20 (6). pp. 353-60. doi:10.1016/j.smim.2008.09.005

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Natural killer (NK) activity has been examined in birds for over 30 years, but evidence that avian NK activity plays crucial roles in disease is only suggestive. In chickens, NK activity is mediated by TCR0 cells in the intestinal epithelium, but elsewhere subsets of alphabeta and gammadelta T cells (NKT cells) may be more important. There are few lectin-like NK receptor genes, located in the genomic region syntenic with the natural killer complex (NKC) as well as the major histocompatibility complex (MHC). In contrast, a huge number of Ig-like receptor genes are located in a region syntenic with the leukocyte receptor complex (LRC).

Item Type: Article
Article Type: Article
Uncontrolled Keywords: REF2014 Submission.
Subjects: Q Science > QH Natural history > QH301 Biology
Q Science > QH Natural history > QH426 Genetics
Q Science > QR Microbiology > QR180 Immunology
Divisions: Schools and Research Institutes > School of Education and Science
Research Priority Areas: Place, Environment and Community
Depositing User: Sally Rogers
Date Deposited: 10 Mar 2015 12:05
Last Modified: 31 Aug 2023 08:59
URI: https://eprints.glos.ac.uk/id/eprint/1998

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