The effects of acute leucine or leucine–glutamine co-ingestion on recovery from eccentrically biased exercise

Waldron, Mark, Ralph, Cameron, Jeffries, Owen, Tallent, Jamie, Theis, Nicola ORCID: 0000-0002-0775-1355 and Patterson, Stephen David (2018) The effects of acute leucine or leucine–glutamine co-ingestion on recovery from eccentrically biased exercise. Amino Acids, 50 (7). pp. 831-839. doi:10.1007/s00726-018-2565-z

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Abstract

This study investigated the effects of leucine or leucine + glutamine supplementation on recovery from eccentric exercise. In a double-blind independent groups design, 23 men were randomly assigned to a leucine (0.087 g/kg; n = 8), leucine + glutamine (0.087 g/kg + glutamine 0.3 g/kg; n = 8) or placebo (0.3 g/kg maltodextrin; n = 7) group. Participants performed 5 sets of drop jumps, with each set comprising 20 repetitions. Isometric knee-extensor strength, counter-movement jump (CMJ) height, delayed-onset muscle soreness (DOMS) and creatine kinase (CK) were measured at baseline, 1, 24, 48 h and 72 h post-exercise. There was a time × group interaction for isometric strength, CMJ and CK (P < 0.05), with differences between the leucine + glutamine and placebo group at 48 h and 72 h for strength (P = 0.013; d = 1.43 and P < 0.001; d = 2.06), CMJ (P = 0.008; d = 0.87 and P = 0.019; d = 1.17) and CK at 24 h (P = 0.012; d = 0.54) and 48 h (P = 0.010; d = 1.37). The leucine group produced higher strength at 72 h compared to placebo (P = 0.007; d = 1.65) and lower CK at 24 h (P = 0.039; d = 0.63) and 48 h (P = 0.022; d = 1.03). Oral leucine or leucine + glutamine increased the rate of recovery compared to placebo after eccentric exercise. These findings highlight potential benefits of co-ingesting these amino acids to ameliorate recovery.

Item Type:	Article
Article Type:	Article
Uncontrolled Keywords:	Amino acids; Muscle damage; Recovery; Supplementation; Exercise
Subjects:	R Medicine > RC Internal medicine > RC1200 Sports Medicine
Divisions:	Schools and Research Institutes > School of Education and Science
Research Priority Areas:	Health, Life Sciences, Sport and Wellbeing
Depositing User:	Susan Turner
Date Deposited:	24 May 2018 15:02
Last Modified:	31 Aug 2023 09:08
URI:	https://eprints.glos.ac.uk/id/eprint/5665

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