Exercise Induced Bronchoconstriction: A Comparison of two Provocation Tests for the Screening of Athletes

Ffoulkes, Joseph L (2015) Exercise Induced Bronchoconstriction: A Comparison of two Provocation Tests for the Screening of Athletes. Masters thesis, University of Gloucestershire.

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BACKGROUND: Exercise induced bronchoconstriction (EIB) affects a large number of athletes, with rates within literature between 7% to 50% for elite athletes (Dickinson et al., 2006; Falvey et al., 2010). Two provocation methods for the diagnosis of EIB include an exercise challenge test (ECT) and a eucapnic voluntary hyperpnoea (EVH) test. Previous research has compared the airway response to ECT to EVH but has often failed to ensure that the ECT is conducted according to standardised guidelines (ATS., 1999; Trumper et al., 2009; Stickland et al., 2010). PURPOSE: Therefore, the aim of this study was to compare the airway responses to ECT and EVH following standardised guidelines. METHODS: In a randomised order and on separate days, seventeen participants completed an ECT and an EVH test. Participants were all University level athletes or professional rugby league player (Age 25 ± 2 yr.; height 1.81 ± 0.06 m; mass 85.4 ± 13.7 kg) recruited via open enquiry to the study. The ECT procedure followed the American Thoracic Society (ATS) protocol, whilst the EVH test followed the procedures recommended by Anderson et al. (2001). Spirometry was performed prior to and at 0, 3, 5, 10, 15, 20, and 30 min post challenge. A positive EIB diagnosis was regarded as a ≥10% decrease in forced expired ventilation over one second (FEV1). RESULTS: Nine participants experienced a fall in FEV1 ≥10%, with five having falls ≥10% in both provocation tests. Two participants experienced falls in the ECT alone and EVH alone respectively. Out of the nine participants, only two had a previous history of asthma. There was no significant difference in the peak ΔFEV1 between the two provocation tests (p=0.143). CONCLUSION: In summation, athletes should be tested for EIB, with both the ECT and EVH being acceptable methods, although our results are inconclusive due to poor agreement and limitations. Future research should aim to have a greater number of participants.

Item Type: Thesis (Masters)
Thesis Advisors:
Thesis AdvisorEmailURL
How, Stephenshow@glos.ac.ukhttps://www.glos.ac.uk/staff/profile/stephen-how/
Fryer, Simonsfryer@glos.ac.ukhttps://www.glos.ac.uk/staff/profile/simon-fryer/
Uncontrolled Keywords: Exercise induced bronchoconstriction (EIB)
Subjects: R Medicine > RC Internal medicine > RC1200 Sports Medicine
Divisions: Schools and Research Institutes > School of Education and Science
Depositing User: Susan Turner
Date Deposited: 22 Jul 2016 11:59
Last Modified: 31 Aug 2023 09:09
URI: https://eprints.glos.ac.uk/id/eprint/3789

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