The effect of cardiorespiratory fitness and habitual physical activity on cardiovascular responses to 2-hours of uninterrupted sitting

Paterson, Craig ORCID: 0000-0003-3125-9712, Stone, Keeron J. ORCID: 0000-0001-6572-7874, Turner, Louise A ORCID: 0000-0003-0847-2232, Moinuddin, Arsalan ORCID: 0000-0002-4242-1714, Stoner, Lee ORCID: 0000-0002-0682-2270 and Fryer, Simon M ORCID: 0000-0003-0376-0104 (2024) The effect of cardiorespiratory fitness and habitual physical activity on cardiovascular responses to 2-hours of uninterrupted sitting. Journal of Applied Physiology, 136 (5). pp. 1087-1096. doi:10.1152/japplphysiol.00361.2023

Text 13833 Paterson et al (2024) The effect of cardiorespiratory fitness and habitual physical activity on cardiovascular responses to.pdf - Accepted Version Restricted to Repository staff only until 5 March 2025. (Publisher Embargo). Available under License All Rights Reserved. Download (481kB)

Abstract

Abstract Prolonged uninterrupted sitting of >3-hours has been shown to acutely cause central and peripheral cardiovascular dysfunction. However, individuals rarely sit uninterrupted for >2-hours, and the cardiovascular response to this time is currently unknown. In addition, whilst increased cardiorespiratory fitness (CRF) and habitual physical activity (HPA) are independently associated with improvements in central and peripheral cardiovascular function, it remains unclear whether they influence the response to uninterrupted sitting. This study sought to 1) determine whether 2-hours of uninterrupted sitting acutely impairs carotid-femoral pulse wave velocity (cfPWV), femoral ankle PWV (faPWV), and central and peripheral blood pressure, and (2) to investigate the associations between CRF and HPA versus PWV changes during uninterrupted sitting. Following 2-hours of uninterrupted sitting, faPWV significantly increased (mean difference [MD] = 0.26 m·s-1, standard error [SE] = 0.10, p = 0.013) as did diastolic blood pressure (MD = 2.83 mmHg, SE = 1.08, p = 0.014), however cfPWV did not significantly change. Whilst our study shows 2-hours uninterrupted sitting significantly impairs faPWV, neither CRF (r = 0.105, p = 0.595) nor HPA (r = -0.228, p = 0.253) were associated with the increases.

Item Type:	Article
Article Type:	Article
Additional Information:	Accepted Version 12m Institutional Repository Must link to publisher version with DOI Embargo12 Months Copyright OwnerPublishers LocationInstitutional Repository ConditionsMust link to publisher version with DOI
Uncontrolled Keywords:	Prolonged sitting; sedentary behaviour; arterial stiffness; cardiorespiratory fitness; physical activity
Subjects:	R Medicine > R Medicine (General)
Divisions:	Schools and Research Institutes > School of Education and Science
Research Priority Areas:	Health, Life Sciences, Sport and Wellbeing
Depositing User:	Charlotte Crutchlow
Date Deposited:	19 Mar 2024 14:53
Last Modified:	20 Nov 2024 13:09
URI:	https://eprints.glos.ac.uk/id/eprint/13833

University Staff: Request a correction | Repository Editors: Update this record