The Clinical and Theranostic Values of Activated Leukocyte Cell Adhesion Molecule (ALCAM)/CD166 in Human Solid Cancers

Yang, Yiming, Sanders, Andrew ORCID: 0000-0002-7997-5286, Dou, Q. Ping, Jiang, David G., Li, Amber Xinyu and Jiang, Wen G. (2021) The Clinical and Theranostic Values of Activated Leukocyte Cell Adhesion Molecule (ALCAM)/CD166 in Human Solid Cancers. Cancers, 13 (20). ART 5187. doi:10.3390/cancers13205187

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Abstract

Activated leukocyte cell adhesion molecule (ALCAM), also known as CD166, is a cell adhesion protein that is found in multiple cell types. ALCAM has multiple and diverse roles in various physiological and pathological conditions, including inflammation and cancer. There has been compelling evidence of ALCAM’s prognostic value in solid cancers, indicating that it is a potential therapeutic target. The present article overviews the recent findings and progress in ALCAM and its involvement in cancer, with a primary focus on its clinical connections in cancer and therapeutic values.

Item Type:	Article
Article Type:	Article
Uncontrolled Keywords:	Activated leukocyte cell adhesion molecule; ALCAM; CD166; Cancer; Prognosis; Survival; Therapeutic targets
Subjects:	R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Divisions:	Schools and Research Institutes > School of Education and Science
Research Priority Areas:	Place, Environment and Community
Depositing User:	Anna Kerr
Date Deposited:	28 Jul 2022 11:15
Last Modified:	16 Oct 2023 10:13
URI:	https://eprints.glos.ac.uk/id/eprint/11409

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