DNA repair and gene editing: the director’s cut

Doughty, Kelly and Baldock, Robert A ORCID: 0000-0002-4649-2966 (2021) DNA repair and gene editing: the director’s cut. Biochemist, 43 (6). pp. 16-20. doi:10.1042/bio_2021_184

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Abstract

Novelists and screenwriters have bombarded our imaginations with the idea of genetic engineering. From superhero origin stories to theme parks inhabited by dinosaurs, the prospect of re-writing the genetic code has inspired many and raised many ethical questions. The potential for these tools in medicine and biological sciences to prevent genetic diseases is readily being explored. Recent successes include destruction of simian immunodeficiency virus DNA from infected rhesus macaque monkeys (synonymous to the human immunodeficiency virus). The diverse power of these tools is also helping to control mosquito populations and supress the spread of malaria. New gene-editing tools have made genome editing faster, more accurate and cheaper than ever before, but how do they work? And how do we know whether the desired edits will be made?

Item Type:	Article
Article Type:	Article
Subjects:	Q Science > Q Science (General) Q Science > QH Natural history > QH426 Genetics
Divisions:	Schools and Research Institutes > School of Education and Science
Research Priority Areas:	Place, Environment and Community
Depositing User:	Robbie Baldock
Date Deposited:	06 Dec 2021 13:07
Last Modified:	31 Aug 2023 08:57
URI:	https://eprints.glos.ac.uk/id/eprint/10437

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