Against the tide: the role of bacterial adhesion in host colonization

Stones, Daniel H ORCID: 0000-0002-8981-7943 and Krachler, A. M. (2016) Against the tide: the role of bacterial adhesion in host colonization. Biochemical Society Transactions, 44 (6). pp. 1571-1580. ISSN 0300-5127

[img]
Preview
Text (Published version)
6066 - Stones - 2016 - Against the tide.pdf - Published Version
Available under License Creative Commons Attribution 4.0.

Download (561kB) | Preview

Abstract

Evolving under the constant exposure to an abundance of diverse microbial life, the human body has developed many ways of defining the boundaries between self and non-self. Many physical and immunological barriers to microbial invasion exist, and yet bacteria have found a multitude of ways to overcome these, initiate interactions with and colonize the human host. Adhesion to host cells and tissues is a key feature allowing bacteria to persist in an environment under constant flux and to initiate transient or permanent symbioses with the host. This review discusses reasons why adhesion is such a seemingly indispensable requirement for bacteria–host interactions, and whether bacteria can bypass the need to adhere and still persist. It further outlines open questions about the role of adhesion in bacterial colonization and persistence within the host.

Item Type: Article
Article Type: Article
Subjects: Q Science > QR Microbiology
Divisions: Schools and Research Institutes > School of Natural & Social Sciences
Research Priority Areas: Environmental Dynamics & Governance
Depositing User: Daniel Stones
Date Deposited: 09 Oct 2018 10:41
Last Modified: 11 Oct 2018 04:22
URI: http://eprints.glos.ac.uk/id/eprint/6066

University Staff: Request a correction | Repository Editors: Update this record

University Of Gloucestershire

Bookmark and Share

Find Us On Social Media:

Social Media Icons Facebook Twitter Google+ YouTube Pinterest Linkedin

Other University Web Sites

University of Gloucestershire, The Park, Cheltenham, Gloucestershire, GL50 2RH. Telephone +44 (0)844 8010001.