Minimal muscle damage after a marathon and no influence of beetroot juice on inflammation and recovery

Clifford, Tom and Allerton, Dean M and Brown, Meghan A and Harper, Liam and Horsburgh, Steven and Keane, Karen M and Stevenson, Emma J and Howatson, Glyn (2017) Minimal muscle damage after a marathon and no influence of beetroot juice on inflammation and recovery. Applied Physiology, Nutrition and Metabolism, 42 (3). pp. 263-270. ISSN 1715-5312

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Abstract

This study examined whether beetroot juice (BTJ) would attenuate inflammation and muscle damage following a marathon. Using a double blind, independent group design, 34 runners (each having completed ca. ∼16 previous marathons) consumed either BTJ or an isocaloric placebo (PLA) for 3 days following a marathon. Maximal isometric voluntary contractions (MIVC), countermovement jumps (CMJ), muscle soreness, serum cytokines, leucocytosis, creatine kinase (CK), high sensitivity C-reactive protein (hs-CRP), and aspartate aminotransferase (AST) were measured pre, post, and 2 days after the marathon. CMJ and MIVC were reduced after the marathon (P < 0.05), but no group differences were observed (P > 0.05). Muscle soreness was increased in the day after the marathon (BTJ; 45 ± 48 vs. PLA; 46 ± 39 mm) and had returned to baseline by day 2, irrespective of supplementation (P = 0.694). Cytokines (interleukin-6; IL-6, interleukin-8, tumour necrosis factor-α) were increased immediately post-marathon but apart from IL-6 had returned to baseline values by day 1 post. No interaction effects were evident for IL-6 (P = 0.213). Leucocytes increased 1.7-fold after the race and remained elevated 2 days post, irrespective of supplement (P < 0.0001). CK peaked at 1 day post marathon (BTJ: 965 ± 967, and PLA: 1141 ± 979 IU·L−1) and like AST and hs-CRP, was still elevated 2 days after the marathon (P < 0.05); however, no group differences were present for these variables. Beetroot juice did not attenuate inflammation or reduce muscle damage following a marathon, possibly because most of these indices were not markedly different from baseline values in the days after the marathon.

Item Type: Article
Article Type: Article
Uncontrolled Keywords: Exercise recovery; betalains; running; marathon; Functional foods; neuromuscular function.
Subjects: G Geography. Anthropology. Recreation > GV Recreation Leisure > GV557 Sports > GV1060 Track and field athletics
G Geography. Anthropology. Recreation > GV Recreation Leisure > GV557 Sports
R Medicine > RC Internal medicine > RC1200 Sports Medicine
Divisions: Schools and Research Institutes > School of Sport & Exercise > Sport and Exercise
Research Priority Areas: Sport, Exercise, Health & Wellbeing
Depositing User: Anne Pengelly
Date Deposited: 07 Nov 2016 14:59
Last Modified: 24 Sep 2017 04:04
URI: http://eprints.glos.ac.uk/id/eprint/4149

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