Rogers, Sally L and Shaw, Iain and Ross, Norman and Nair, Venugopal and Rothwell, Lisa and Kaufman, Jim and Kaiser, Pete (2003) Analysis of part of the chicken Rfp-Y region reveals two novel lectin genes, the first complete genomic sequence of a class I alpha-chain gene, a truncated class II beta-chain gene, and a large CR1 repeat. Immunogenetics, 55 (2). pp. 100-8. ISSN 0093-7711Full text not available from this repository.
The Rfp-Y region lies on the same microchromosome as the B-F/B-L region of the B complex, yet in contrast to the latter it is poorly characterised. To date it has been shown to contain at least two class I alpha-chain ( Y-F) genes, a class II B-chain gene and a C-type lectin-like gene. We describe the sequencing and analysis of some 20 kb of the Rfp-Y region, and identify several new genes. These include two novel C-type lectin-like genes ( Y-Lec1 and Y-Lec2) that differ strongly from the previously described C-type lectin-like gene found in the Rfp-Y region. We describe a complete genomic sequence of a class I alpha-chain ( Y-F) gene and its promoter from the Rfp-Y region. The predicted cDNA from this gene has high homology to the previously reported Y-F cDNAs. The promoter contains an altered enhancer A element. This portion of the Rfp-Y region also contains a truncated class II B-chain ( Y-LB) gene, as well as a large chicken repeat 1 (CR1) element.
|Subjects:||Q Science > QH Natural history > QH426 Genetics
Q Science > QR Microbiology > QR180 Immunology
|Divisions:||Schools and Research Institutes > School of Natural & Social Sciences > Environmental Sciences|
|Research Priority Areas:||Environmental Dynamics & Governance|
|Depositing User:||Sally Rogers|
|Date Deposited:||06 Mar 2015 15:22|
|Last Modified:||16 Mar 2016 15:24|