Hemispheric lateralisation and immune function: A systematic review of human research

Sumner, Rachel C ORCID: 0000-0002-2421-7146, Parton, Andrew, Nowicky, Alexander V, Kishore, Uday and Gidron, Yori (2011) Hemispheric lateralisation and immune function: A systematic review of human research. Journal of Neuroimmunology, 240-24. pp. 1-12. doi:10.1016/j.jneuroim.2011.08.017

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Abstract

Past studies examined relationships between hemispheric lateralisation (HL) and immune system functioning. However, there has been no up-dated systematic review of this research area. This article reviews relevant published studies, evaluates study quality and effect sizes. Eleven studies were selected: three revealing a relationship between weaker left hemisphere function and poorer immune function, three describing a relationship between weaker right hemisphere function and stronger immune functioning, and five describing both relationships. Mean effect-size of the studies was r = 0.536 (range 0.280–0.866). Collectively, studies point at left-HL and stronger immunity relationships. Limitations, mechanisms and clinical implications are discussed.

Item Type: Article
Article Type: Article
Uncontrolled Keywords: Hemispheric lateralisation; Immune function; Brain to immune communication; Immunomodulation; Humans; Diseases
Subjects: B Philosophy. Psychology. Religion > BF Psychology
R Medicine > RC Internal medicine > RC321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: Schools and Research Institutes > School of Health and Social Care
Research Priority Areas: Health, Life Sciences, Sport and Wellbeing
Depositing User: Rachel Sumner
Date Deposited: 25 May 2016 16:25
Last Modified: 27 Jul 2023 15:48
URI: https://eprints.glos.ac.uk/id/eprint/3545

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