A 24 hour naproxen dose on gastrointestinal distress and performance during cycling in the heat

Emerson, Dawn M., Davis, J. Mark, Chen, Stephen CL., Torres-McGehee, Toni M., Pfeifer, Craig E. ORCID: 0000-0002-0635-4956, Emerson, Charles C., Bivona, Joseph D. and Stone, Justin V. (2020) A 24 hour naproxen dose on gastrointestinal distress and performance during cycling in the heat. Sports Medicine and Health Science, 2 (1). pp. 19-24. doi:10.1016/j.smhs.2020.02.003

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Abstract

Using a double-blind, randomized and counterbalanced, cross-over design, we assessed naproxen's effects on gastrointestinal (GI) distress and performance in eleven volunteers (6 male, 5 female). Participants completed 4 trials: 1) placebo and ambient); 2) placebo and heat; 3) naproxen and ambient; and 4) naproxen and heat. Independent variables were one placebo or 220 mg naproxen pill every 8 h (h) for 24 h and ambient (22.7 ± 1.8°C) or thermal environment (35.7 ± 1.3°C). Participants cycled 80 min at a steady heart rate then 10 min for maximum distance. Perceived exertion was measured throughout cycling. Gastrointestinal distress was assessed pre-, during, post-, 3 h post-, and 24 h post-cycling using a GI index for upper, lower, and systemic symptoms. No statistically significant differences occurred between conditions at any time for GI symptoms or perceived exertion, distance, or heart rate during maximum effort. A 24 h naproxen dose did not significantly affect performance or cause more frequent or serious GI distress when participants were euhydrated and cycling at moderate intensity in a thermal environment.

Item Type: Article
Article Type: Article
Uncontrolled Keywords: NSAID; Gastrointestinal bleeding; Heart rate; Perceived exertion; Cycling
Subjects: G Geography. Anthropology. Recreation > GV Recreation Leisure > GV557 Sports > GV1040 Cycling. Bicycling. Motorcycling
R Medicine > RC Internal medicine > RC1200 Sports Medicine
Divisions: Schools and Research Institutes > School of Sport and Exercise > Applied Sport & Exercise Sciences
Research Priority Areas: Sport, Exercise, Health & Wellbeing
Depositing User: Susan Turner
Date Deposited: 17 Jul 2020 13:11
Last Modified: 29 Jul 2020 08:45
URI: http://eprints.glos.ac.uk/id/eprint/8567

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