Assessment of cardiovascular risk and vascular age in overweight/obese adults with primary hypertension:EXERDIET-HTA Study

Gorostegi-Anduaga, I and Pérez-Asenjo, J and Aispuru, R and Fryer, Simon M and Alonso-Colmenero, A and Romaratezabala, E and Maldonado-Martin, Sara (2017) Assessment of cardiovascular risk and vascular age in overweight/obese adults with primary hypertension:EXERDIET-HTA Study. Blood Pressure Monitoring, 22 (3). pp. 154-160. ISSN 1359-5237

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Objectives: Hypertension (HTN), obesity and low cardiorespiratory fitness (CRF) are associated with an increased risk of a cardiovascular event. Taking part overweight/obese individuals with HTN the aims of the current study were: to estimate cardiovascular risk (CVR) and vascular age (VA) profiles analyzing potential sex differences; to determine whether VA is higher than chronological age (CA) and, whether CVR is associated with a low level of CRF. Methods: Overweight/obese non-Hispanic white participants (n=209; 141 men and 68 women) with primary HTN had their CVR and VA determined using the New Pooled Cohort Risk Equations and The Framingham method, respectively. Considering values of peak oxygen uptake, participants were divided into tertiles for each sex. Results: The CVR, but not VA (p=0.339), was higher (p<0.001) in men compared to women irrespective of age. Irrespective of sex VA was higher than CA (p<0.001). Age and body mass index were higher (p<0.05) in the low CRF group compared to other groups. There were no differences in CVR (p=0.907) and VA (p=1.643) when values were separated into CRF groups. Conclusions: Pooled Cohort Equations could underestimate the risk of suffering a cardiovascular event in the following 10 years in overweight/obese non-Hispanic white women with HTN compared to men. The VA appears to be a useful tool in communicating CVR in this population irrespective of sex. The CRF alone may not be enough to moderate the CVR.

Item Type: Article
Article Type: Article
Uncontrolled Keywords: Cardiovascular disease; Chronological age, Cardio-respiratory fitness
Subjects: R Medicine > RC Internal medicine > RC1200 Sports Medicine
Divisions: Schools and Research Institutes > School of Sport & Exercise > Sport and Exercise
Research Priority Areas: Sport, Exercise, Health & Wellbeing
Depositing User: Anne Pengelly
Date Deposited: 15 Feb 2017 12:20
Last Modified: 15 Jan 2018 20:43

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