A Comparison of Capillary, Venous, and Salivary Cortisol Sampling After Intense Exercise

Fryer, Simon M and Dickson, Tabitha and Hillier, Stephen and Stoner, Lee and Scarrott, Carl and Draper, Nick (2014) A Comparison of Capillary, Venous, and Salivary Cortisol Sampling After Intense Exercise. International Journal of Sports Physiology and Performance, 9 (6). pp. 973-977. ISSN 1555-0265

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Abstract

Venipuncture is expensive, invasive, and impractical for many sport-science and clinical-based settings. Salivary free cortisol is often cited as a noninvasive practical alternative. However, when cortisol concentrations exceed the corticosteroid-binding globulin (CBG) point of 500 nmol/L, a lack of agreement between salivary and venous blood cortisol has been found. Alternatively, capillary blood may present a minimally invasive, cost-effective, and practical surrogate for determining cortisol concentration. PURPOSE: The aim of this study was to determine whether cortisol concentrations sampled from capillary blood and saliva accurately reflect those found in venous blood across a large range of concentrations after intense exercise. METHODS: Eleven healthy aerobically trained male subjects were recruited. Capillary, salivary, and venous blood samples were collected before and after (immediately and 5, 10, 15, and 20 min after) a treadmill VO(2) max test. RESULTS: Capillary and venous concentrations increased at a similar rate after exercise (Cohen d.14-.33), increasing up to 15 min postexercise before a decline was seen. Salivary cortisol values increased at a slower rate than venous and capillary cortisol but continued to increase 15 min postexercise (Cohen d .19-.47 and .09-.72, respectively). CONCLUSIONS: Capillary cortisol accurately reflects concentrations assayed from venous blood across a range of values below and above the CBG binding point. Capillary sampling provides a minimally invasive, cost-effective, practical surrogate for assessment of hypothalamic-pituitary-gland function.

Item Type: Article
Article Type: Article
Subjects: G Geography. Anthropology. Recreation > GV Recreation Leisure > GV557 Sports
R Medicine > RC Internal medicine > RC1200 Sports Medicine
Divisions: Faculty of Business, Computing and Applied Sciences > School of Sport & Exercise > Sport and Exercise
Research Priority Areas: Sport, Exercise, Health & Wellbeing
Depositing User: Anne Pengelly
Date Deposited: 20 Jul 2015 13:30
Last Modified: 02 Nov 2016 16:59
URI: http://eprints.glos.ac.uk/id/eprint/2470

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